Drug interactions
Bexarotene + Ertugliflozin-sitagliptin
Severity: Moderate
Bexarotene and Ertugliflozin-sitagliptin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bexarotene may enhance insulin sensitivity and could add to the glucose-lowering action of antidiabetic drugs. Hypoglycemia has not been seen with bexarotene alone, and sitagliptin carries low intrinsic hypoglycemia risk. The effect is largely theoretical.
What this interaction means in plain words
Bexarotene and Ertugliflozin-sitagliptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexarotene belongs to Oncology; Ertugliflozin-sitagliptin belongs to Endocrine.
Why it happens
Additive pharmacodynamic glucose lowering via insulin-sensitizing effects of bexarotene.
What to do
Monitor blood glucose when bexarotene is started, and reduce antidiabetic doses if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Bexarotene and Ertugliflozin-sitagliptin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Ertugliflozin-sitagliptin
Other interactions of Bexarotene
- Bexarotene + Gemfibrozil Major
- Bexarotene + Lorlatinib Major
- Alogliptin-pioglitazone + Bexarotene Moderate
- Amobarbital + Bexarotene Moderate
- Aprepitant + Bexarotene Moderate
- Axitinib + Bexarotene Moderate
Frequently asked questions
Can I take Bexarotene with Ertugliflozin-sitagliptin?
MediHelp rates the interaction as moderate. Bexarotene and Ertugliflozin-sitagliptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexarotene may enhance insulin sensitivity and could add to the glucose-lowering action of antidiabetic drugs. Hypoglycemia has not been seen with bexarotene alone, and sitagliptin carries low intrinsic hypoglycemia risk. The effect is largely theoretical.
How serious is the interaction between Bexarotene and Ertugliflozin-sitagliptin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when bexarotene is started, and reduce antidiabetic doses if hypoglycemia occurs.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
