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Drug interactions

Ertugliflozin-sitagliptin + Marijuana

Severity: Minor

Ertugliflozin-sitagliptin and Marijuana: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cannabis may increase appetite and food intake and has been associated with changes in glycemic control. A reliable clinically significant effect on sitagliptin or ertugliflozin has not been established.

What this interaction means in plain words

Ertugliflozin-sitagliptin and Marijuana have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

The mechanism is not well established; possible indirect effects via appetite and metabolic changes.

What to do

No dose change is needed. Monitor blood glucose in regular cannabis users and counsel about diet.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ertugliflozin-sitagliptin with Marijuana?

MediHelp rates the interaction as minor. Ertugliflozin-sitagliptin and Marijuana have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cannabis may increase appetite and food intake and has been associated with changes in glycemic control. A reliable clinically significant effect on sitagliptin or ertugliflozin has not been established.

How serious is the interaction between Ertugliflozin-sitagliptin and Marijuana?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor blood glucose in regular cannabis users and counsel about diet.

What other medicines interact with Ertugliflozin-sitagliptin?

MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.

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