Drug interactions
Ethacrynic acid + Metoprolol
Severity: Minor
Ethacrynic acid and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Loop diuretics and beta-blockers are often combined and have additive blood pressure lowering. Ethacrynic acid can cause hypokalemia and volume depletion, which can potentiate hypotension.
What this interaction means in plain words
Ethacrynic acid and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethacrynic acid belongs to Cardiovascular; Metoprolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects from diuresis and beta-blockade.
What to do
Monitor blood pressure, volume status and serum electrolytes, especially at initiation or dose changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Ethacrynic acid with Metoprolol?
MediHelp rates the interaction as minor. Ethacrynic acid and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Loop diuretics and beta-blockers are often combined and have additive blood pressure lowering. Ethacrynic acid can cause hypokalemia and volume depletion, which can potentiate hypotension.
How serious is the interaction between Ethacrynic acid and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, volume status and serum electrolytes, especially at initiation or dose changes.
What other medicines interact with Metoprolol?
MediHelp also lists interactions of Metoprolol with, for example, Thioridazine, Amifostine, Amiodarone. The full list is on the Metoprolol page.
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