Drug interactions
Ethanol + Silodosin
Severity: Minor
Ethanol and Silodosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol causes vasodilation and can add to the blood pressure lowering and orthostatic effects of silodosin. This may cause dizziness, lightheadedness or fainting, especially when standing up or at treatment start.
What this interaction means in plain words
Ethanol and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic hypotensive effect from alpha-1 adrenergic blockade and alcohol-induced vasodilation.
What to do
Advise patients to limit alcohol, particularly in the first weeks of therapy, and to rise slowly from sitting or lying positions.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Silodosin
- Atazanavir + Silodosin Contraindicated
- Conivaptan + Silodosin Contraindicated
- Darunavir + Silodosin Contraindicated
- Fosamprenavir + Silodosin Contraindicated
- Indinavir + Silodosin Contraindicated
- Itraconazole + Silodosin Contraindicated
Frequently asked questions
Can I take Ethanol with Silodosin?
MediHelp rates the interaction as minor. Ethanol and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Alcohol causes vasodilation and can add to the blood pressure lowering and orthostatic effects of silodosin. This may cause dizziness, lightheadedness or fainting, especially when standing up or at treatment start.
How serious is the interaction between Ethanol and Silodosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to limit alcohol, particularly in the first weeks of therapy, and to rise slowly from sitting or lying positions.
What other medicines interact with Silodosin?
MediHelp also lists interactions of Silodosin with, for example, Atazanavir, Conivaptan, Darunavir. The full list is on the Silodosin page.
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