Drug interactions
Ethinyl estradiol-drospirenone + Labetalol
Severity: Minor
Ethinyl estradiol-drospirenone and Labetalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Non-selective beta-blockers can slightly raise serum potassium by impairing cellular uptake. With drospirenone the combined effect is usually small, but it could matter in patients with renal impairment or other potassium-raising drugs.
What this interaction means in plain words
Ethinyl estradiol-drospirenone and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethinyl estradiol-drospirenone belongs to Endocrine; Labetalol belongs to Cardiovascular.
Why it happens
Mild additive effect on potassium: beta-blockade reduces cellular potassium uptake while drospirenone reduces renal excretion.
What to do
Routine use needs no change; check potassium if renal impairment or other potassium-raising drugs are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ethinyl estradiol-drospirenone and Labetalol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-drospirenone Major
- Amobarbital + Ethinyl estradiol-drospirenone Major
Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Frequently asked questions
Can I take Ethinyl estradiol-drospirenone with Labetalol?
MediHelp rates the interaction as minor. Ethinyl estradiol-drospirenone and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Non-selective beta-blockers can slightly raise serum potassium by impairing cellular uptake. With drospirenone the combined effect is usually small, but it could matter in patients with renal impairment or other potassium-raising drugs.
How serious is the interaction between Ethinyl estradiol-drospirenone and Labetalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Routine use needs no change; check potassium if renal impairment or other potassium-raising drugs are present.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
