Drug interactions
Ethinyl estradiol-drospirenone + Liraglutide
Severity: Minor
Ethinyl estradiol-drospirenone and Liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combined oral contraceptives can mildly impair glucose tolerance and could blunt glucose lowering in patients treated with liraglutide. Liraglutide may also delay gastric emptying and, if vomiting or diarrhea occurs, reduce contraceptive absorption, though labeling reports no clinically relevant change in exposure.
What this interaction means in plain words
Ethinyl estradiol-drospirenone and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethinyl estradiol-drospirenone belongs to Endocrine; Liraglutide belongs to Endocrine.
Why it happens
Estrogen and progestin effects reduce insulin sensitivity, while delayed gastric emptying may affect oral hormone absorption.
What to do
Monitor glycemic control when starting the contraceptive. Advise backup contraception if persistent vomiting or diarrhea occurs on liraglutide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ethinyl estradiol-drospirenone and Liraglutide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-drospirenone Major
- Amobarbital + Ethinyl estradiol-drospirenone Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Ethinyl estradiol-drospirenone with Liraglutide?
MediHelp rates the interaction as minor. Ethinyl estradiol-drospirenone and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Combined oral contraceptives can mildly impair glucose tolerance and could blunt glucose lowering in patients treated with liraglutide. Liraglutide may also delay gastric emptying and, if vomiting or diarrhea occurs, reduce contraceptive absorption, though labeling reports no clinically relevant change in exposure.
How serious is the interaction between Ethinyl estradiol-drospirenone and Liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control when starting the contraceptive. Advise backup contraception if persistent vomiting or diarrhea occurs on liraglutide.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
