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Drug interactions

Etomidate + Haloperidol

Severity: Moderate

Etomidate and Haloperidol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Etomidate is an intravenous anesthetic induction agent, and haloperidol may enhance its sedative and hypotensive effects. The combination is manageable in monitored anesthesia settings.

What this interaction means in plain words

Etomidate and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Etomidate belongs to Central Nervous System; Haloperidol belongs to Central Nervous System.

Evidence level: Low

Why it happens

Additive CNS depression.

What to do

Anesthesia providers should titrate the etomidate dose to effect and monitor hemodynamics.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Etomidate with Haloperidol?

MediHelp rates the interaction as moderate. Etomidate and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Etomidate is an intravenous anesthetic induction agent, and haloperidol may enhance its sedative and hypotensive effects. The combination is manageable in monitored anesthesia settings.

How serious is the interaction between Etomidate and Haloperidol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Anesthesia providers should titrate the etomidate dose to effect and monitor hemodynamics.

What other medicines interact with Haloperidol?

MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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