Drug interactions
Etomidate + Metoprolol
Severity: Minor
Etomidate and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etomidate is relatively hemodynamically stable, but combined with beta-blockade it may still lead to hypotension and blunted compensatory tachycardia during induction.
What this interaction means in plain words
Etomidate and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etomidate belongs to Central Nervous System; Metoprolol belongs to Cardiovascular.
Why it happens
Additive hemodynamic effects; beta-blockade limits reflex tachycardia.
What to do
Monitor blood pressure and heart rate during induction and have vasopressors available.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Other interactions of Etomidate
- Alprazolam + Etomidate Moderate
- Amitriptyline + Etomidate Moderate
- Amobarbital + Etomidate Moderate
- Azelastine + Etomidate Moderate
- Baclofen + Etomidate Moderate
- Brompheniramine + Etomidate Moderate
Frequently asked questions
Can I take Etomidate with Metoprolol?
MediHelp rates the interaction as minor. Etomidate and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etomidate is relatively hemodynamically stable, but combined with beta-blockade it may still lead to hypotension and blunted compensatory tachycardia during induction.
How serious is the interaction between Etomidate and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during induction and have vasopressors available.
What other medicines interact with Metoprolol?
MediHelp also lists interactions of Metoprolol with, for example, Thioridazine, Amifostine, Amiodarone. The full list is on the Metoprolol page.
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