Drug interactions
Etravirine + Haloperidol
Severity: Moderate
Etravirine and Haloperidol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etravirine is a mild to moderate inducer of CYP3A4 and may lower haloperidol concentrations, potentially reducing antipsychotic control. Etravirine may also affect other pathways, so the magnitude is uncertain.
What this interaction means in plain words
Etravirine and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Etravirine belongs to Anti Virals; Haloperidol belongs to Central Nervous System.
Why it happens
Induction of CYP3A4 by etravirine increases haloperidol metabolism.
What to do
Monitor psychiatric response and increase haloperidol dose if symptoms re-emerge.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Etravirine
- Efavirenz + Etravirine Contraindicated
- Etravirine + Isavuconazole Contraindicated
- Amobarbital + Etravirine Major
- Apalutamide + Etravirine Major
- Carbamazepine + Etravirine Major
- Cobicistat + Etravirine Major
Frequently asked questions
Can I take Etravirine with Haloperidol?
MediHelp rates the interaction as moderate. Etravirine and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Etravirine is a mild to moderate inducer of CYP3A4 and may lower haloperidol concentrations, potentially reducing antipsychotic control. Etravirine may also affect other pathways, so the magnitude is uncertain.
How serious is the interaction between Etravirine and Haloperidol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor psychiatric response and increase haloperidol dose if symptoms re-emerge.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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