Drug interactions
Felodipine + Sotalol
Severity: Minor
Felodipine and Sotalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination produces additive blood pressure lowering. Beta-blockade offsets felodipine reflex tachycardia, but hypotension or bradycardia may occur in some patients, especially those with impaired ventricular function.
What this interaction means in plain words
Felodipine and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Sotalol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic effects of beta-blockade and calcium channel blocker vasodilation.
What to do
Monitor blood pressure and heart rate when starting or changing doses. Adjust dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Sotalol?
MediHelp rates the interaction as minor. Felodipine and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The combination produces additive blood pressure lowering. Beta-blockade offsets felodipine reflex tachycardia, but hypotension or bradycardia may occur in some patients, especially those with impaired ventricular function.
How serious is the interaction between Felodipine and Sotalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or changing doses. Adjust dose if symptomatic hypotension occurs.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
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