Drug interactions
Fenofibrate + Tenofovir df
Severity: Minor
Fenofibrate and Tenofovir df: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
No well-established interaction exists between these drugs. Both have renal elimination components and tenofovir can cause renal toxicity, which could affect fibrate handling in renal impairment. The legacy description does not match a mechanism I can confirm.
What this interaction means in plain words
Fenofibrate and Tenofovir df have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; possible additive renal effects in patients with reduced kidney function.
What to do
Monitor renal function periodically, and adjust the fenofibrate dose if creatinine clearance declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenofibrate
- Atorvastatin + Fenofibrate Moderate
- Cholestyramine + Fenofibrate Moderate
- Cholic acid + Fenofibrate Moderate
- Colchicine + Fenofibrate Moderate
- Colestipol + Fenofibrate Moderate
- Cyclosporine + Fenofibrate Moderate
Frequently asked questions
Can I take Fenofibrate with Tenofovir df?
MediHelp rates the interaction as minor. Fenofibrate and Tenofovir df have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No well-established interaction exists between these drugs. Both have renal elimination components and tenofovir can cause renal toxicity, which could affect fibrate handling in renal impairment. The legacy description does not match a mechanism I can confirm.
How serious is the interaction between Fenofibrate and Tenofovir df?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function periodically, and adjust the fenofibrate dose if creatinine clearance declines.
What other medicines interact with Fenofibrate?
MediHelp also lists interactions of Fenofibrate with, for example, Atorvastatin, Cholestyramine, Cholic acid. The full list is on the Fenofibrate page.
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