Drug interactions
Ferric citrate + Moxifloxacin
Severity: Moderate
Ferric citrate and Moxifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ferric citrate releases trivalent iron in the gut, which binds moxifloxacin and reduces its absorption. This can lower antibiotic concentrations and risk treatment failure.
What this interaction means in plain words
Ferric citrate and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferric citrate belongs to Miscellaneous; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Chelation of moxifloxacin by ferric iron in the gastrointestinal tract, forming poorly absorbed complexes.
What to do
Give oral moxifloxacin at least 4 hours before or 8 hours after ferric citrate, in line with the moxifloxacin labelling for iron-containing products.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Other interactions of Ferric citrate
- Ciprofloxacin + Ferric citrate Moderate
- Deferiprone + Ferric citrate Moderate
- Doxycycline + Ferric citrate Moderate
- Ferric citrate + Gemifloxacin Moderate
- Ferric citrate + Levofloxacin Moderate
- Ferric citrate + Ofloxacin Moderate
Frequently asked questions
Can I take Ferric citrate with Moxifloxacin?
MediHelp rates the interaction as moderate. Ferric citrate and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ferric citrate releases trivalent iron in the gut, which binds moxifloxacin and reduces its absorption. This can lower antibiotic concentrations and risk treatment failure.
How serious is the interaction between Ferric citrate and Moxifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral moxifloxacin at least 4 hours before or 8 hours after ferric citrate, in line with the moxifloxacin labelling for iron-containing products.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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