Drug interactions
Finerenone + Vinblastine
Severity: Minor
Finerenone and Vinblastine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vinblastine is a CYP3A4 substrate with weak inhibitory effect at most, so a clinically meaningful rise in finerenone is unlikely. Finerenone can raise potassium, so potassium monitoring is relevant anyway.
What this interaction means in plain words
Finerenone and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finerenone belongs to Cardiovascular; Vinblastine belongs to Oncology.
Why it happens
Possible weak CYP3A4 competition reducing finerenone metabolism.
What to do
Monitor serum potassium and renal function as for routine finerenone therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Finerenone and Vinblastine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Vinblastine
Other interactions of Finerenone
- Carbamazepine + Finerenone Contraindicated
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
Frequently asked questions
Can I take Finerenone with Vinblastine?
MediHelp rates the interaction as minor. Finerenone and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vinblastine is a CYP3A4 substrate with weak inhibitory effect at most, so a clinically meaningful rise in finerenone is unlikely. Finerenone can raise potassium, so potassium monitoring is relevant anyway.
How serious is the interaction between Finerenone and Vinblastine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function as for routine finerenone therapy.
What other medicines interact with Vinblastine?
MediHelp also lists interactions of Vinblastine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Atazanavir. The full list is on the Vinblastine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
