Drug interactions
Finerenone + Ziprasidone
Severity: Minor
Finerenone and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Finerenone is metabolised mainly by CYP3A4. Ziprasidone is not a clinically relevant CYP3A4 inhibitor, so a meaningful rise in finerenone exposure is unlikely.
What this interaction means in plain words
Finerenone and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finerenone belongs to Cardiovascular; Ziprasidone belongs to Central Nervous System.
Why it happens
No established CYP3A4 inhibition by ziprasidone; the interaction is theoretical.
What to do
No dose adjustment is needed. Monitor serum potassium as for routine finerenone therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Other interactions of Finerenone
- Carbamazepine + Finerenone Contraindicated
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
Frequently asked questions
Can I take Finerenone with Ziprasidone?
MediHelp rates the interaction as minor. Finerenone and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Finerenone is metabolised mainly by CYP3A4. Ziprasidone is not a clinically relevant CYP3A4 inhibitor, so a meaningful rise in finerenone exposure is unlikely.
How serious is the interaction between Finerenone and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor serum potassium as for routine finerenone therapy.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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