Drug interactions
Flavoxate + Trazodone
Severity: Minor
Flavoxate and Trazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trazodone has weak anticholinergic activity, so additive effects with flavoxate are likely small. Mild dry mouth or constipation may occur, and sedation or dizziness may add in older adults.
What this interaction means in plain words
Flavoxate and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flavoxate belongs to Genitourinary; Trazodone belongs to Central Nervous System.
Why it happens
Weak additive antimuscarinic effects.
What to do
No dose change is usually needed; monitor older patients for dizziness, confusion and urinary symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flavoxate
- Clozapine + Flavoxate Major
- Abobotulinumtoxina + Flavoxate Moderate
- Aclidinium + Flavoxate Moderate
- Amantadine + Flavoxate Moderate
- Amitriptyline + Flavoxate Moderate
- Amoxapine + Flavoxate Moderate
Other interactions of Trazodone
- Arsenic trioxide + Trazodone Contraindicated
- Ibutilide + Trazodone Contraindicated
- Isocarboxazid + Trazodone Contraindicated
- Levoketoconazole + Trazodone Contraindicated
- Methylene blue + Trazodone Contraindicated
- Phenelzine + Trazodone Contraindicated
Frequently asked questions
Can I take Flavoxate with Trazodone?
MediHelp rates the interaction as minor. Flavoxate and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trazodone has weak anticholinergic activity, so additive effects with flavoxate are likely small. Mild dry mouth or constipation may occur, and sedation or dizziness may add in older adults.
How serious is the interaction between Flavoxate and Trazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor older patients for dizziness, confusion and urinary symptoms.
What other medicines interact with Flavoxate?
MediHelp also lists interactions of Flavoxate with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Flavoxate page.
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