Drug interactions
Flibanserin + Tecovirimat
Severity: Minor
Flibanserin and Tecovirimat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tecovirimat weakly inhibits CYP2C19 and weakly induces CYP3A4, so its net effect on flibanserin is small and unpredictable. Use is typically short-term.
What this interaction means in plain words
Flibanserin and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flibanserin belongs to Genitourinary; Tecovirimat belongs to Miscellaneous.
Why it happens
Weak CYP2C19 inhibition and weak CYP3A4 induction by tecovirimat.
What to do
Monitor for sedation or dizziness during the short tecovirimat course; no dose adjustment is routinely needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Tecovirimat
- Bosentan + Tecovirimat Moderate
- Cyclosporin + Tecovirimat Moderate
- Darunavir + Tecovirimat Moderate
- Ethinyl estradiol-drospirenone + Tecovirimat Moderate
- Ethinyl estradiol-levonorgestrel + Tecovirimat Moderate
- Glimepiride-pioglitazone + Tecovirimat Moderate
Frequently asked questions
Can I take Flibanserin with Tecovirimat?
MediHelp rates the interaction as minor. Flibanserin and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tecovirimat weakly inhibits CYP2C19 and weakly induces CYP3A4, so its net effect on flibanserin is small and unpredictable. Use is typically short-term.
How serious is the interaction between Flibanserin and Tecovirimat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation or dizziness during the short tecovirimat course; no dose adjustment is routinely needed.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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