Drug interactions
Fluphenazine + Teduglutide
Severity: Moderate
Fluphenazine and Teduglutide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide increases intestinal fluid absorption and may enhance absorption of oral drugs. Exposure to oral fluphenazine could therefore rise, with greater sedation or extrapyramidal effects.
What this interaction means in plain words
Fluphenazine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluphenazine belongs to Central Nervous System; Teduglutide belongs to Endocrine.
Why it happens
Teduglutide improves intestinal absorptive capacity, which may increase absorption of oral medications.
What to do
Monitor clinical response and adverse effects of fluphenazine after teduglutide is started or stopped. Adjust the fluphenazine dose if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluphenazine
- Arsenic trioxide + Fluphenazine Contraindicated
- Dofetilide + Fluphenazine Contraindicated
- Fluphenazine + Ibutilide Contraindicated
- Fluphenazine + Pimozide Contraindicated
- Adagrasib + Fluphenazine Major
- Alfentanil + Fluphenazine Major
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Fluphenazine with Teduglutide?
MediHelp rates the interaction as moderate. Fluphenazine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide increases intestinal fluid absorption and may enhance absorption of oral drugs. Exposure to oral fluphenazine could therefore rise, with greater sedation or extrapyramidal effects.
How serious is the interaction between Fluphenazine and Teduglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response and adverse effects of fluphenazine after teduglutide is started or stopped. Adjust the fluphenazine dose if needed.
What other medicines interact with Fluphenazine?
MediHelp also lists interactions of Fluphenazine with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Fluphenazine page.
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