Drug interactions
Fluvoxamine + Selinexor
Severity: Minor
Fluvoxamine and Selinexor: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Selinexor commonly causes dizziness, fatigue and confusion, and fluvoxamine can add sedation or CNS effects. No specific pharmacokinetic interaction is established.
What this interaction means in plain words
Fluvoxamine and Selinexor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluvoxamine belongs to Central Nervous System; Selinexor belongs to Oncology.
Why it happens
No established mechanism; possible additive CNS adverse effects.
What to do
Monitor for dizziness, confusion and sedation and counsel patients about driving and fall risk.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Other interactions of Selinexor
- Aldesleukin + Selinexor Moderate
- Alprazolam + Selinexor Moderate
- Amitriptyline + Selinexor Moderate
- Amobarbital + Selinexor Moderate
- Aripiprazole + Selinexor Moderate
- Asenapine + Selinexor Moderate
Frequently asked questions
Can I take Fluvoxamine with Selinexor?
MediHelp rates the interaction as minor. Fluvoxamine and Selinexor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Selinexor commonly causes dizziness, fatigue and confusion, and fluvoxamine can add sedation or CNS effects. No specific pharmacokinetic interaction is established.
How serious is the interaction between Fluvoxamine and Selinexor?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for dizziness, confusion and sedation and counsel patients about driving and fall risk.
What other medicines interact with Fluvoxamine?
MediHelp also lists interactions of Fluvoxamine with, for example, Agomelatine, Alosetron, Fezolinetant. The full list is on the Fluvoxamine page.
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