Drug interactions
Formoterol-mometasone + Goserelin
Severity: Moderate
Formoterol-mometasone and Goserelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with goserelin can prolong the QT interval, and formoterol may contribute additional QT effects and hypokalemia. The combination could raise the risk of torsades de pointes in susceptible patients.
What this interaction means in plain words
Formoterol-mometasone and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Goserelin belongs to Endocrine.
Why it happens
Additive QT prolongation: androgen deprivation alters cardiac repolarization and beta-2 agonists can prolong QT and lower potassium.
What to do
Review baseline ECG and electrolytes in patients with cardiac risk factors, and correct hypokalemia. Avoid adding further QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Goserelin
Frequently asked questions
Can I take Formoterol-mometasone with Goserelin?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgen deprivation therapy with goserelin can prolong the QT interval, and formoterol may contribute additional QT effects and hypokalemia. The combination could raise the risk of torsades de pointes in susceptible patients.
How serious is the interaction between Formoterol-mometasone and Goserelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review baseline ECG and electrolytes in patients with cardiac risk factors, and correct hypokalemia. Avoid adding further QT-prolonging drugs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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