Drug interactions
Formoterol-mometasone + Hydrochlorothiazide
Severity: Moderate
Formoterol-mometasone and Hydrochlorothiazide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics, beta-2 agonists and corticosteroids all tend to lower serum potassium. Combined use can cause significant hypokalemia, with a risk of arrhythmias in vulnerable patients.
What this interaction means in plain words
Formoterol-mometasone and Hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Additive hypokalemia from renal potassium loss with thiazides, intracellular potassium shift with formoterol and corticosteroid potassium wasting.
What to do
Monitor serum potassium, particularly after starting or increasing doses, and supplement or use a potassium-sparing agent if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Hydrochlorothiazide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Other interactions of Hydrochlorothiazide
Frequently asked questions
Can I take Formoterol-mometasone with Hydrochlorothiazide?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide diuretics, beta-2 agonists and corticosteroids all tend to lower serum potassium. Combined use can cause significant hypokalemia, with a risk of arrhythmias in vulnerable patients.
How serious is the interaction between Formoterol-mometasone and Hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium, particularly after starting or increasing doses, and supplement or use a potassium-sparing agent if needed.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
