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Drug interactions

Formoterol-mometasone + Midodrine

Severity: Moderate

Formoterol-mometasone and Midodrine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Midodrine is an alpha1-agonist that raises blood pressure, and formoterol has sympathomimetic cardiovascular effects. Used together they may add to increases in blood pressure and heart rate.

What this interaction means in plain words

Formoterol-mometasone and Midodrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Formoterol-mometasone belongs to Respiratory; Midodrine belongs to Miscellaneous.

Evidence level: Low

Why it happens

Additive sympathomimetic effects from alpha1-adrenergic vasoconstriction and beta-adrenergic stimulation.

What to do

Monitor blood pressure and heart rate, particularly in patients with cardiovascular disease. Reduce doses if hypertension or tachyarrhythmia develops.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Formoterol-mometasone with Midodrine?

MediHelp rates the interaction as moderate. Formoterol-mometasone and Midodrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Midodrine is an alpha1-agonist that raises blood pressure, and formoterol has sympathomimetic cardiovascular effects. Used together they may add to increases in blood pressure and heart rate.

How serious is the interaction between Formoterol-mometasone and Midodrine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, particularly in patients with cardiovascular disease. Reduce doses if hypertension or tachyarrhythmia develops.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

Full monographs, dosing and an interaction checker in the MediHelp app

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