Drug interactions
Formoterol-mometasone + Ozanimod
Severity: Minor
Formoterol-mometasone and Ozanimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol can prolong the QT interval and raise heart rate, while ozanimod can slow heart rate at initiation. Together they may increase the risk of rhythm disturbances, although the clinical risk with inhaled formoterol at usual doses is small.
What this interaction means in plain words
Formoterol-mometasone and Ozanimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Formoterol-mometasone belongs to Respiratory; Ozanimod belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic effects on cardiac conduction and repolarisation (beta-agonist QT effect versus S1P-receptor-mediated bradycardia).
What to do
Obtain a baseline ECG before starting ozanimod in patients using formoterol and seek cardiology advice if there is significant QT prolongation or arrhythmia history. Monitor heart rate and symptoms during ozanimod initiation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol-mometasone
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Ozanimod?
MediHelp rates the interaction as minor. Formoterol-mometasone and Ozanimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Formoterol can prolong the QT interval and raise heart rate, while ozanimod can slow heart rate at initiation. Together they may increase the risk of rhythm disturbances, although the clinical risk with inhaled formoterol at usual doses is small.
How serious is the interaction between Formoterol-mometasone and Ozanimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG before starting ozanimod in patients using formoterol and seek cardiology advice if there is significant QT prolongation or arrhythmia history. Monitor heart rate and symptoms during ozanimod initiation.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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