Drug interactions
Formoterol-mometasone + Trimipramine
Severity: Moderate
Formoterol-mometasone and Trimipramine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tricyclic antidepressants can potentiate the cardiovascular effects of beta-2 agonists and both can prolong QTc. This may increase the risk of arrhythmias and tachycardia.
What this interaction means in plain words
Formoterol-mometasone and Trimipramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Trimipramine belongs to Central Nervous System.
Why it happens
Additive QT prolongation and enhanced adrenergic cardiovascular effects with tricyclic noradrenaline reuptake inhibition.
What to do
Monitor heart rate, rhythm and QTc, especially with high formoterol doses or cardiac disease; consider alternatives if arrhythmia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Trimipramine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Other interactions of Trimipramine
- Disopyramide + Trimipramine Contraindicated
- Dofetilide + Trimipramine Contraindicated
- Ibutilide + Trimipramine Contraindicated
- Isocarboxazid + Trimipramine Contraindicated
- Pentamidine + Trimipramine Contraindicated
- Phenelzine + Trimipramine Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Trimipramine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Trimipramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tricyclic antidepressants can potentiate the cardiovascular effects of beta-2 agonists and both can prolong QTc. This may increase the risk of arrhythmias and tachycardia.
How serious is the interaction between Formoterol-mometasone and Trimipramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, rhythm and QTc, especially with high formoterol doses or cardiac disease; consider alternatives if arrhythmia occurs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
