Drug interactions
Fosinopril + Lanthanum carbonate
Severity: Moderate
Fosinopril and Lanthanum carbonate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum is a polyvalent cation that can bind to fosinopril in the gut and may reduce its absorption. This could lessen blood pressure control.
What this interaction means in plain words
Fosinopril and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fosinopril belongs to Cardiovascular; Lanthanum carbonate belongs to Miscellaneous.
Why it happens
Chelation or binding of fosinopril by lanthanum in the gastrointestinal tract reduces absorption.
What to do
Give fosinopril at least 2 hours before or after lanthanum carbonate and monitor blood pressure.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fosinopril
- Aliskiren + Fosinopril Contraindicated
- Fosinopril + Protein a column Contraindicated
- Fosinopril + Sacubitril / valsartan Contraindicated
- Fosinopril + Sacubitril-valsartan Contraindicated
- Amifostine + Fosinopril Major
- Amiloride + Fosinopril Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Fosinopril with Lanthanum carbonate?
MediHelp rates the interaction as moderate. Fosinopril and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanthanum is a polyvalent cation that can bind to fosinopril in the gut and may reduce its absorption. This could lessen blood pressure control.
How serious is the interaction between Fosinopril and Lanthanum carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give fosinopril at least 2 hours before or after lanthanum carbonate and monitor blood pressure.
What other medicines interact with Fosinopril?
MediHelp also lists interactions of Fosinopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Fosinopril page.
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