Drug interactions
Doxycycline + Lanthanum carbonate
Severity: Moderate
Doxycycline and Lanthanum carbonate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum is a polyvalent cation that can bind oral doxycycline in the gut and decrease its absorption. This may lead to subtherapeutic antibiotic levels.
What this interaction means in plain words
Doxycycline and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxycycline belongs to Anti Bacterial; Lanthanum carbonate belongs to Miscellaneous.
Why it happens
Chelation or binding of doxycycline by lanthanum cations in the gastrointestinal tract.
What to do
Take doxycycline at least 2 hours before or after lanthanum carbonate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Doxycycline
- Acitretin + Doxycycline Contraindicated
- Aminolevulinic acid + Doxycycline Major
- Cholera vaccine + Doxycycline Major
- Doxycycline + Isotretinoin Major
- Doxycycline + Methoxyflurane Major
- Doxycycline + Microbiota Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Doxycycline with Lanthanum carbonate?
MediHelp rates the interaction as moderate. Doxycycline and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanthanum is a polyvalent cation that can bind oral doxycycline in the gut and decrease its absorption. This may lead to subtherapeutic antibiotic levels.
How serious is the interaction between Doxycycline and Lanthanum carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take doxycycline at least 2 hours before or after lanthanum carbonate.
What other medicines interact with Doxycycline?
MediHelp also lists interactions of Doxycycline with, for example, Acitretin, Aminolevulinic acid, Cholera vaccine. The full list is on the Doxycycline page.
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