Drug interactions
Ciprofloxacin + Lanthanum carbonate
Severity: Moderate
Ciprofloxacin and Lanthanum carbonate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum is a polyvalent cation that binds oral ciprofloxacin in the gut and reduces its absorption. Lower antibiotic levels could lead to treatment failure.
What this interaction means in plain words
Ciprofloxacin and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Lanthanum carbonate belongs to Miscellaneous.
Why it happens
Chelation of ciprofloxacin by lanthanum in the gastrointestinal tract, reducing oral bioavailability.
What to do
Give oral ciprofloxacin at least 2 hours before or 6 hours after lanthanum. Intravenous ciprofloxacin is not affected.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Ciprofloxacin with Lanthanum carbonate?
MediHelp rates the interaction as moderate. Ciprofloxacin and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanthanum is a polyvalent cation that binds oral ciprofloxacin in the gut and reduces its absorption. Lower antibiotic levels could lead to treatment failure.
How serious is the interaction between Ciprofloxacin and Lanthanum carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after lanthanum. Intravenous ciprofloxacin is not affected.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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