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Drug interactions

Chloroquine + Lanthanum carbonate

Severity: Moderate

Chloroquine and Lanthanum carbonate: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Lanthanum binds to chloroquine in the gut and can reduce its absorption. This may lower chloroquine effectiveness.

What this interaction means in plain words

Chloroquine and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Chloroquine belongs to Anti Parasitic; Lanthanum carbonate belongs to Miscellaneous.

Evidence level: Moderate

Why it happens

Chelation or adsorption of chloroquine by lanthanum in the GI tract, reducing absorption.

What to do

Give chloroquine at least 2 hours before or after lanthanum carbonate.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chloroquine with Lanthanum carbonate?

MediHelp rates the interaction as moderate. Chloroquine and Lanthanum carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanthanum binds to chloroquine in the gut and can reduce its absorption. This may lower chloroquine effectiveness.

How serious is the interaction between Chloroquine and Lanthanum carbonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give chloroquine at least 2 hours before or after lanthanum carbonate.

What other medicines interact with Chloroquine?

MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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