Drug interactions
Fosinopril + Maraviroc
Severity: Moderate
Fosinopril and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc, a CCR5 antagonist, is associated with postural hypotension, particularly in patients with renal impairment or on antihypertensives. Combined use with fosinopril may increase the risk of dizziness and falls.
What this interaction means in plain words
Fosinopril and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fosinopril belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive hypotensive effects; maraviroc-related postural hypotension mechanism is not fully defined.
What to do
Monitor orthostatic blood pressure when starting maraviroc and counsel patients about dizziness; adjust the antihypertensive dose if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fosinopril
- Aliskiren + Fosinopril Contraindicated
- Fosinopril + Protein a column Contraindicated
- Fosinopril + Sacubitril / valsartan Contraindicated
- Fosinopril + Sacubitril-valsartan Contraindicated
- Amifostine + Fosinopril Major
- Amiloride + Fosinopril Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Fosinopril with Maraviroc?
MediHelp rates the interaction as moderate. Fosinopril and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc, a CCR5 antagonist, is associated with postural hypotension, particularly in patients with renal impairment or on antihypertensives. Combined use with fosinopril may increase the risk of dizziness and falls.
How serious is the interaction between Fosinopril and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor orthostatic blood pressure when starting maraviroc and counsel patients about dizziness; adjust the antihypertensive dose if needed.
What other medicines interact with Fosinopril?
MediHelp also lists interactions of Fosinopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Fosinopril page.
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