Drug interactions
Fostemsavir + Indacaterol
Severity: Moderate
Fostemsavir and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fostemsavir has caused QT prolongation at supratherapeutic doses, and long-acting beta-agonists can also affect cardiac repolarization. Combined use may add to arrhythmia risk, mainly in patients with other risk factors.
What this interaction means in plain words
Fostemsavir and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fostemsavir belongs to Anti Virals; Indacaterol belongs to Respiratory.
Why it happens
Additive QT interval prolongation through different pharmacodynamic effects on cardiac repolarization.
What to do
Use at recommended fostemsavir doses and correct potassium and magnesium. Obtain an ECG if the patient has congenital long QT, cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Fostemsavir
- Apalutamide + Fostemsavir Contraindicated
- Carbamazepine + Fostemsavir Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Fostemsavir + Mitotane Contraindicated
- Fostemsavir + Phenytoin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
Frequently asked questions
Can I take Fostemsavir with Indacaterol?
MediHelp rates the interaction as moderate. Fostemsavir and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fostemsavir has caused QT prolongation at supratherapeutic doses, and long-acting beta-agonists can also affect cardiac repolarization. Combined use may add to arrhythmia risk, mainly in patients with other risk factors.
How serious is the interaction between Fostemsavir and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use at recommended fostemsavir doses and correct potassium and magnesium. Obtain an ECG if the patient has congenital long QT, cardiac disease or other QT-prolonging drugs.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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