Drug interactions
Furosemide + Labetalol
Severity: Minor
Furosemide and Labetalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Labetalol and furosemide both lower blood pressure, so combined use may cause excessive hypotension or orthostatic dizziness. Beta-blockade has only a small potassium-raising tendency compared with the diuretic's potassium loss.
What this interaction means in plain words
Furosemide and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Furosemide belongs to Cardiovascular; Labetalol belongs to Cardiovascular.
Why it happens
Additive hypotensive effects from alpha/beta-blockade and volume reduction.
What to do
Monitor blood pressure, including standing readings, when starting or titrating either drug. Check serum potassium periodically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Frequently asked questions
Can I take Furosemide with Labetalol?
MediHelp rates the interaction as minor. Furosemide and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Labetalol and furosemide both lower blood pressure, so combined use may cause excessive hypotension or orthostatic dizziness. Beta-blockade has only a small potassium-raising tendency compared with the diuretic's potassium loss.
How serious is the interaction between Furosemide and Labetalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including standing readings, when starting or titrating either drug. Check serum potassium periodically.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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