Drug interactions
Furosemide + Metoprolol
Severity: Minor
Furosemide and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Furosemide and metoprolol are frequently prescribed together, and the combination produces additive blood pressure lowering. Furosemide-induced hypokalemia is not clearly offset by beta-blockade, and the potassium effects of the pair are of limited clinical significance in most patients.
What this interaction means in plain words
Furosemide and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Furosemide belongs to Cardiovascular; Metoprolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic antihypertensive effect; loop diuretic potassium wasting with small beta-blocker effects on potassium redistribution.
What to do
Monitor blood pressure and serum potassium periodically, particularly when starting or titrating either drug. Correct hypokalemia if it develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Frequently asked questions
Can I take Furosemide with Metoprolol?
MediHelp rates the interaction as minor. Furosemide and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Furosemide and metoprolol are frequently prescribed together, and the combination produces additive blood pressure lowering. Furosemide-induced hypokalemia is not clearly offset by beta-blockade, and the potassium effects of the pair are of limited clinical significance in most patients.
How serious is the interaction between Furosemide and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum potassium periodically, particularly when starting or titrating either drug. Correct hypokalemia if it develops.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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