Drug interactions
Ganaxolone + Vilazodone
Severity: Moderate
Ganaxolone and Vilazodone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ganaxolone causes somnolence and sedation, and vilazodone can add to drowsiness. Combined use may impair alertness and psychomotor function.
What this interaction means in plain words
Ganaxolone and Vilazodone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ganaxolone belongs to Central Nervous System; Vilazodone belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Monitor for excessive sedation and counsel on driving and avoiding alcohol. Reduce doses if sedation is problematic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vilazodone
- Isocarboxazid + Vilazodone Contraindicated
- Methylene blue + Vilazodone Contraindicated
- Phenelzine + Vilazodone Contraindicated
- Rasagiline + Vilazodone Contraindicated
- Selegiline transdermal + Vilazodone Contraindicated
- Selegiline + Vilazodone Contraindicated
Other interactions of Ganaxolone
Frequently asked questions
Can I take Ganaxolone with Vilazodone?
MediHelp rates the interaction as moderate. Ganaxolone and Vilazodone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ganaxolone causes somnolence and sedation, and vilazodone can add to drowsiness. Combined use may impair alertness and psychomotor function.
How serious is the interaction between Ganaxolone and Vilazodone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and counsel on driving and avoiding alcohol. Reduce doses if sedation is problematic.
What other medicines interact with Vilazodone?
MediHelp also lists interactions of Vilazodone with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Vilazodone page.
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