Drug interactions
Gemifloxacin + Indacaterol-glycopyrronium
Severity: Moderate
Gemifloxacin and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gemifloxacin can prolong the QT interval, and indacaterol may add modest repolarization effects or hypokalemia. The combination may raise the risk of ventricular arrhythmias in susceptible patients.
What this interaction means in plain words
Gemifloxacin and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Gemifloxacin belongs to Anti Bacterial; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization.
What to do
Check ECG and correct electrolytes in patients with cardiac risk factors. Consider an alternative antibiotic with less QT effect when risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Frequently asked questions
Can I take Gemifloxacin with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Gemifloxacin and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gemifloxacin can prolong the QT interval, and indacaterol may add modest repolarization effects or hypokalemia. The combination may raise the risk of ventricular arrhythmias in susceptible patients.
How serious is the interaction between Gemifloxacin and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and correct electrolytes in patients with cardiac risk factors. Consider an alternative antibiotic with less QT effect when risk is high.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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