Drug interactions
Gemifloxacin + Selinexor
Severity: Minor
Gemifloxacin and Selinexor: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Selinexor commonly causes dizziness, confusion and other neurological effects, and fluoroquinolones can cause CNS effects too. The combination may increase neurological adverse effects, but the interaction is largely theoretical.
What this interaction means in plain words
Gemifloxacin and Selinexor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gemifloxacin belongs to Anti Bacterial; Selinexor belongs to Oncology.
Why it happens
Possible additive CNS adverse effects; no established pharmacokinetic mechanism.
What to do
Counsel patients about dizziness and confusion and advise caution with driving. Monitor for neurological symptoms and review the antibiotic if they develop.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Gemifloxacin and Selinexor, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Other interactions of Selinexor
- Aldesleukin + Selinexor Moderate
- Alprazolam + Selinexor Moderate
- Amitriptyline + Selinexor Moderate
- Amobarbital + Selinexor Moderate
- Aripiprazole + Selinexor Moderate
- Asenapine + Selinexor Moderate
Frequently asked questions
Can I take Gemifloxacin with Selinexor?
MediHelp rates the interaction as minor. Gemifloxacin and Selinexor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Selinexor commonly causes dizziness, confusion and other neurological effects, and fluoroquinolones can cause CNS effects too. The combination may increase neurological adverse effects, but the interaction is largely theoretical.
How serious is the interaction between Gemifloxacin and Selinexor?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about dizziness and confusion and advise caution with driving. Monitor for neurological symptoms and review the antibiotic if they develop.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
