Drug interactions
Gentamicin + Magnesium hydroxide
Severity: Minor
Gentamicin and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gentamicin causes renal magnesium wasting and may lead to hypomagnesemia. Magnesium hydroxide is a magnesium source, so the effect is largely offset.
What this interaction means in plain words
Gentamicin and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gentamicin belongs to Anti Bacterial; Magnesium hydroxide belongs to Gastrointestinal Tract.
Why it happens
Aminoglycoside tubular toxicity increases urinary magnesium excretion.
What to do
Monitor serum magnesium and renal function during gentamicin therapy and replace magnesium as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Gentamicin with Magnesium hydroxide?
MediHelp rates the interaction as minor. Gentamicin and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gentamicin causes renal magnesium wasting and may lead to hypomagnesemia. Magnesium hydroxide is a magnesium source, so the effect is largely offset.
How serious is the interaction between Gentamicin and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium and renal function during gentamicin therapy and replace magnesium as needed.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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