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Drug interactions

Glucagon + Umeclidinium-vilanterol

Severity: Minor

Glucagon and Umeclidinium-vilanterol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Glucagon labeling notes that anticholinergics may add to its inhibition of gastrointestinal motility. This concern applies mainly to diagnostic use of glucagon; inhaled umeclidinium has low systemic exposure, so the effect is likely small.

What this interaction means in plain words

Glucagon and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Glucagon belongs to Endocrine; Umeclidinium-vilanterol belongs to Respiratory.

Evidence level: Low

Why it happens

Additive inhibition of gastrointestinal motility through antimuscarinic action and glucagon effect.

What to do

No routine action is needed. Monitor for abdominal discomfort or constipation if glucagon is used for GI imaging.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Glucagon with Umeclidinium-vilanterol?

MediHelp rates the interaction as minor. Glucagon and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon labeling notes that anticholinergics may add to its inhibition of gastrointestinal motility. This concern applies mainly to diagnostic use of glucagon; inhaled umeclidinium has low systemic exposure, so the effect is likely small.

How serious is the interaction between Glucagon and Umeclidinium-vilanterol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor for abdominal discomfort or constipation if glucagon is used for GI imaging.

What other medicines interact with Umeclidinium-vilanterol?

MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.

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