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Drug interactions

Griseofulvin + Montelukast

Severity: Minor

Griseofulvin and Montelukast: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Griseofulvin is a weak CYP inducer and could slightly lower montelukast exposure. The effect is expected to be small.

What this interaction means in plain words

Griseofulvin and Montelukast have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Griseofulvin belongs to Anti Fungals; Montelukast belongs to Respiratory.

Evidence level: Low

Why it happens

Weak induction of hepatic CYP enzymes by griseofulvin increases montelukast metabolism.

What to do

No dose change is needed. Monitor asthma control during long courses.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Griseofulvin with Montelukast?

MediHelp rates the interaction as minor. Griseofulvin and Montelukast have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a weak CYP inducer and could slightly lower montelukast exposure. The effect is expected to be small.

How serious is the interaction between Griseofulvin and Montelukast?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor asthma control during long courses.

What other medicines interact with Montelukast?

MediHelp also lists interactions of Montelukast with, for example, Apalutamide, Carbamazepine, Deferasirox. The full list is on the Montelukast page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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