Drug interactions
Haloperidol + Indacaterol-glycopyrronium
Severity: Moderate
Haloperidol and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Haloperidol prolongs the QT interval and can cause torsades de pointes, and indacaterol may add to repolarization effects or lower potassium. Haloperidol also has some anticholinergic activity that may add to that of glycopyrronium.
What this interaction means in plain words
Haloperidol and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Haloperidol belongs to Central Nervous System; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization and mild additive antimuscarinic effects.
What to do
Obtain ECG and correct potassium and magnesium in patients with cardiac risk factors. Use the lowest effective haloperidol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Haloperidol with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Haloperidol and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Haloperidol prolongs the QT interval and can cause torsades de pointes, and indacaterol may add to repolarization effects or lower potassium. Haloperidol also has some anticholinergic activity that may add to that of glycopyrronium.
How serious is the interaction between Haloperidol and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain ECG and correct potassium and magnesium in patients with cardiac risk factors. Use the lowest effective haloperidol dose.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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