Drug interactions
Hydrochlorothiazide-lisinopril + Magnesium hydroxide
Severity: Minor
Hydrochlorothiazide-lisinopril and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides promote urinary magnesium wasting, while magnesium hydroxide provides magnesium. The practical effect is small and mostly unimportant with occasional antacid or laxative use.
What this interaction means in plain words
Hydrochlorothiazide-lisinopril and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-lisinopril belongs to Cardiovascular; Magnesium hydroxide belongs to Gastrointestinal Tract.
Why it happens
Thiazide-induced renal magnesium loss may counteract magnesium absorbed from the product.
What to do
No routine action is needed; monitor serum magnesium if the patient has long-term thiazide therapy and symptoms of hypomagnesemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-lisinopril
- Dofetilide + Hydrochlorothiazide-lisinopril Contraindicated
- Hydrochlorothiazide-lisinopril + Sacubitril / valsartan Contraindicated
- Amifostine + Hydrochlorothiazide-lisinopril Major
- Amiloride + Hydrochlorothiazide-lisinopril Major
- Benazepril + Hydrochlorothiazide-lisinopril Major
- Bendroflumethiazide + Hydrochlorothiazide-lisinopril Major
Other interactions of Magnesium hydroxide
Frequently asked questions
Can I take Hydrochlorothiazide-lisinopril with Magnesium hydroxide?
MediHelp rates the interaction as minor. Hydrochlorothiazide-lisinopril and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides promote urinary magnesium wasting, while magnesium hydroxide provides magnesium. The practical effect is small and mostly unimportant with occasional antacid or laxative use.
How serious is the interaction between Hydrochlorothiazide-lisinopril and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor serum magnesium if the patient has long-term thiazide therapy and symptoms of hypomagnesemia.
What other medicines interact with Hydrochlorothiazide-lisinopril?
MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.
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