Drug interactions
Hydrochlorothiazide-olmesartan + Porfimer
Severity: Moderate
Hydrochlorothiazide-olmesartan and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Porfimer is a photosensitizer, and thiazides are also photosensitizing. Patients may have a greater risk of skin phototoxic reactions after porfimer therapy.
What this interaction means in plain words
Hydrochlorothiazide-olmesartan and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydrochlorothiazide-olmesartan belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of porfimer and the thiazide.
What to do
Counsel strict avoidance of sunlight and bright indoor light as directed after porfimer. Consider holding the thiazide combination during the photosensitivity period if feasible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Other interactions of Porfimer
Frequently asked questions
Can I take Hydrochlorothiazide-olmesartan with Porfimer?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-olmesartan and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Porfimer is a photosensitizer, and thiazides are also photosensitizing. Patients may have a greater risk of skin phototoxic reactions after porfimer therapy.
How serious is the interaction between Hydrochlorothiazide-olmesartan and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict avoidance of sunlight and bright indoor light as directed after porfimer. Consider holding the thiazide combination during the photosensitivity period if feasible.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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