Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Porfimer
Severity: Moderate
Amlodipine-olmesartan-hydrochlorothiazide and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide is photosensitizing, and porfimer causes photosensitivity after photodynamic therapy. Use together may increase the risk or severity of skin phototoxic reactions.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects.
What to do
Counsel strict sun and bright light avoidance for the period specified by porfimer labeling. Monitor the skin for burns.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Porfimer
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Porfimer?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide is photosensitizing, and porfimer causes photosensitivity after photodynamic therapy. Use together may increase the risk or severity of skin phototoxic reactions.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict sun and bright light avoidance for the period specified by porfimer labeling. Monitor the skin for burns.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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