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Drug interactions

Hydrochlorothiazide-telmisartan + Maraviroc

Severity: Moderate

Hydrochlorothiazide-telmisartan and Maraviroc: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Maraviroc can cause postural hypotension, particularly in patients with renal impairment or on blood pressure-lowering drugs. Adding telmisartan and hydrochlorothiazide may increase the risk of dizziness and syncope.

What this interaction means in plain words

Hydrochlorothiazide-telmisartan and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Maraviroc belongs to Anti Virals.

Evidence level: Low

Why it happens

Additive pharmacodynamic hypotensive effects.

What to do

Monitor for orthostatic symptoms and blood pressure when starting maraviroc, and review the antihypertensive dose if hypotension occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Hydrochlorothiazide-telmisartan with Maraviroc?

MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, particularly in patients with renal impairment or on blood pressure-lowering drugs. Adding telmisartan and hydrochlorothiazide may increase the risk of dizziness and syncope.

How serious is the interaction between Hydrochlorothiazide-telmisartan and Maraviroc?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for orthostatic symptoms and blood pressure when starting maraviroc, and review the antihypertensive dose if hypotension occurs.

What other medicines interact with Hydrochlorothiazide-telmisartan?

MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.

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