Drug interactions
Hydroxychloroquine + Ipratropium-salbutamol
Severity: Moderate
Hydroxychloroquine and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxychloroquine prolongs the QT interval, and high-dose salbutamol can contribute through tachycardia and hypokalemia. The combination may raise the risk of arrhythmia, especially with other risk factors.
What this interaction means in plain words
Hydroxychloroquine and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydroxychloroquine belongs to Musculoskeletal; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-agonist-related hypokalemia.
What to do
Check potassium and magnesium and obtain an ECG in patients with cardiac disease or other QT-prolonging drugs. Limit salbutamol to the lowest effective dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Hydroxychloroquine and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydroxychloroquine prolongs the QT interval, and high-dose salbutamol can contribute through tachycardia and hypokalemia. The combination may raise the risk of arrhythmia, especially with other risk factors.
How serious is the interaction between Hydroxychloroquine and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and obtain an ECG in patients with cardiac disease or other QT-prolonging drugs. Limit salbutamol to the lowest effective dose.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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