Drug interactions
Imidapril + Torsemide
Severity: Moderate
Imidapril and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Adding imidapril to a loop diuretic can cause marked hypotension, especially at initiation or with volume depletion. Renal function may also decline.
What this interaction means in plain words
Imidapril and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Imidapril belongs to Cardiovascular; Torsemide belongs to Cardiovascular.
Why it happens
Diuretic-induced renin-angiotensin activation is blocked by ACE inhibition, giving additive hypotension and reduced glomerular filtration.
What to do
Monitor blood pressure, creatinine and potassium after starting or titrating, and consider lowering the diuretic dose before starting imidapril in volume-depleted patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Torsemide
Other interactions of Imidapril
- Amiloride + Imidapril Major
- Eplerenone + Imidapril Major
- Imidapril + Lithium Major
- Imidapril + Pregabalin Major
- Imidapril + Spironolactone Major
- Imidapril + Triamterene Major
Frequently asked questions
Can I take Imidapril with Torsemide?
MediHelp rates the interaction as moderate. Imidapril and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Adding imidapril to a loop diuretic can cause marked hypotension, especially at initiation or with volume depletion. Renal function may also decline.
How serious is the interaction between Imidapril and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, creatinine and potassium after starting or titrating, and consider lowering the diuretic dose before starting imidapril in volume-depleted patients.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
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