Drug interactions
Indacaterol + Levofloxacin
Severity: Moderate
Indacaterol and Levofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levofloxacin can prolong the QT interval and indacaterol may add to arrhythmic risk via hypokalemia and tachycardia. The combination may raise the risk of ventricular arrhythmias.
What this interaction means in plain words
Indacaterol and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Levofloxacin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation and beta-2 agonist-induced hypokalemia.
What to do
Check ECG and electrolytes in patients with cardiac disease or other QT-prolonging drugs. Choose a non-QT-prolonging antibiotic if risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Frequently asked questions
Can I take Indacaterol with Levofloxacin?
MediHelp rates the interaction as moderate. Indacaterol and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levofloxacin can prolong the QT interval and indacaterol may add to arrhythmic risk via hypokalemia and tachycardia. The combination may raise the risk of ventricular arrhythmias.
How serious is the interaction between Indacaterol and Levofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes in patients with cardiac disease or other QT-prolonging drugs. Choose a non-QT-prolonging antibiotic if risk is high.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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