Drug interactions
Indacaterol + Prednisone
Severity: Moderate
Indacaterol and Prednisone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both beta-2 agonists and corticosteroids can lower serum potassium. Combined use may cause additive hypokalemia, which can promote arrhythmias, especially with higher steroid doses or hypoxia.
What this interaction means in plain words
Indacaterol and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Prednisone belongs to Endocrine.
Why it happens
Beta-2 stimulated intracellular potassium shift combined with corticosteroid mineralocorticoid-related renal potassium loss.
What to do
Monitor serum potassium in patients on systemic steroids, especially during exacerbations. Replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Frequently asked questions
Can I take Indacaterol with Prednisone?
MediHelp rates the interaction as moderate. Indacaterol and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both beta-2 agonists and corticosteroids can lower serum potassium. Combined use may cause additive hypokalemia, which can promote arrhythmias, especially with higher steroid doses or hypoxia.
How serious is the interaction between Indacaterol and Prednisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on systemic steroids, especially during exacerbations. Replace potassium as needed.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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