Drug interactions
Indacaterol + Quetiapine
Severity: Moderate
Indacaterol and Quetiapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quetiapine can prolong the QT interval, particularly at higher doses or in overdose. Indacaterol may add to arrhythmic risk via cardiac stimulation and hypokalemia.
What this interaction means in plain words
Indacaterol and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Quetiapine belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic QT prolongation with possible beta-2 agonist-induced hypokalemia.
What to do
Monitor QTc in patients with additional risk factors. Maintain normal potassium and magnesium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Indacaterol with Quetiapine?
MediHelp rates the interaction as moderate. Indacaterol and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quetiapine can prolong the QT interval, particularly at higher doses or in overdose. Indacaterol may add to arrhythmic risk via cardiac stimulation and hypokalemia.
How serious is the interaction between Indacaterol and Quetiapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor QTc in patients with additional risk factors. Maintain normal potassium and magnesium.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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