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Drug interactions

Indacaterol-glycopyrronium + Moxifloxacin

Severity: Moderate

Indacaterol-glycopyrronium and Moxifloxacin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Moxifloxacin prolongs the QT interval, and indacaterol may add to this effect and lower potassium. The combination may increase the risk of ventricular arrhythmias.

What this interaction means in plain words

Indacaterol-glycopyrronium and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Indacaterol-glycopyrronium belongs to Respiratory; Moxifloxacin belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Additive QT prolongation with beta-agonist-induced hypokalemia.

What to do

Monitor ECG and electrolytes in patients with cardiac risk factors, or select a non-QT-prolonging antibiotic.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Indacaterol-glycopyrronium with Moxifloxacin?

MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxifloxacin prolongs the QT interval, and indacaterol may add to this effect and lower potassium. The combination may increase the risk of ventricular arrhythmias.

How serious is the interaction between Indacaterol-glycopyrronium and Moxifloxacin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac risk factors, or select a non-QT-prolonging antibiotic.

What other medicines interact with Indacaterol-glycopyrronium?

MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.

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