Drug interactions
Indacaterol-glycopyrronium + Succinylcholine
Severity: Minor
Indacaterol-glycopyrronium and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Succinylcholine is a depolarizing neuromuscular blocker acting at nicotinic receptors, and glycopyrronium acts at muscarinic receptors. Anticholinergics are sometimes given to blunt succinylcholine bradycardia, so a significant interaction is not expected. Beta2-agonists may lower potassium, which can alter responses to depolarizing blockade.
What this interaction means in plain words
Indacaterol-glycopyrronium and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Indacaterol-glycopyrronium belongs to Respiratory; Succinylcholine belongs to Musculoskeletal.
Why it happens
Different receptor targets; no established significant interaction with inhaled glycopyrronium.
What to do
No specific action is needed beyond routine perioperative monitoring. Check potassium if the patient has risk factors for hypokalemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Succinylcholine
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Succinylcholine?
MediHelp rates the interaction as minor. Indacaterol-glycopyrronium and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Succinylcholine is a depolarizing neuromuscular blocker acting at nicotinic receptors, and glycopyrronium acts at muscarinic receptors. Anticholinergics are sometimes given to blunt succinylcholine bradycardia, so a significant interaction is not expected. Beta2-agonists may lower potassium, which can alter responses to depolarizing blockade.
How serious is the interaction between Indacaterol-glycopyrronium and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond routine perioperative monitoring. Check potassium if the patient has risk factors for hypokalemia.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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