Drug interactions
Indapamide + Porfimer
Severity: Moderate
Indapamide and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both indapamide and porfimer can cause photosensitivity. Concurrent use may increase the risk of phototoxic skin reactions during the period after porfimer when patients are highly light sensitive.
What this interaction means in plain words
Indapamide and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indapamide belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of a thiazide-like diuretic and a photodynamic therapy sensitizer.
What to do
Counsel strict light protection after porfimer for the period stated in labeling, and consider withholding indapamide if the clinical situation allows. Watch for skin reactions.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indapamide
Other interactions of Porfimer
Frequently asked questions
Can I take Indapamide with Porfimer?
MediHelp rates the interaction as moderate. Indapamide and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both indapamide and porfimer can cause photosensitivity. Concurrent use may increase the risk of phototoxic skin reactions during the period after porfimer when patients are highly light sensitive.
How serious is the interaction between Indapamide and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict light protection after porfimer for the period stated in labeling, and consider withholding indapamide if the clinical situation allows. Watch for skin reactions.
What other medicines interact with Indapamide?
MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.
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